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Melatonin is a powerful antioxidant protector which is naturally produced in the retina. It is responsible for protection of the cell's DNA, which is the blueprint for the cell's survival. Damage to the DNA is linked to the onset and progression of macular degeneration.1
Blue light suppresses the production of melatonin in the retina, and is the catalyst for the production of drusen deposits on Bruch's membrane.2 Protecting the eyes from blue-light damage, by wearing blue-light filtering sunglasses is strongly recommended by optometrists and ophthalmologists.
1. Zhou, J., Cai, B., Janq, Y.P., Pachydaki, S., Schmidt, A.M., Sparrow, J.R., Mechanisms for the Induction of HNE-MDA- and AGE Adducts, RAGE and VEGF in retinal Pigment Epithelial Cells. Experimental Eye Research,, 2005: Apr. 80(4):567-80.
2. Osborne,N. N., Nash, M. S., Wood, J. P. M., Melatonin Counteracts Ischemia-Induced Apotosis in Human Retinal Pigment Epithelial Cells. Laboratory of Ophthalmology, University of Oxford, United Kingdom. July 29, 1998.
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